A postdoctoral position is immediately available in the laboratories of Drs. Andrew Luster and James Moon at the Center for Immunology and Inflammatory Diseases at Massachusetts General Hospital - Harvard Medical School to study CD4+ T cell responses to SARS-CoV-2 and related coronaviruses. This work is part of a highly collaborative NIH program project spread across several labs in the Boston area to develop next generation pan coronavirus vaccines. Studies will primarily focus on characterization of SARS-CoV-2 antigen-specific CD4+ T cell phenotypes, durability, and cross-reactivity during natural infection and vaccination in human subjects using a variety of T cell assays including AIM (activation-induced marker) expression, peptide:MHC tetramer staining, and single cell RNA-seq transcriptomic and TCR repertoire analyses. Additional studies will involve in vivo modeling of protective immune responses in animals following vaccination with candidate immunogens and modalities.
Candidates must be highly motivated, well organized, technically proficient, critically minded, and able to work independently but collaboratively with others. Candidates must possess a recent PhD, MD, or MD/PhD with a strong background in cellular or molecular immunology. Extra consideration will be given to those with relevant experience with advanced flow cytometry, in vitro T cell assays, mouse modeling, and systems biology.
To apply, email a cover letter describing research interests and career goals, CV, and contact information for 3 references to Dr. James Moon (firstname.lastname@example.org)