Postdoctoral Fellow- Janowitz Lab at Cold Spring Harbor Laboratory

  • Postdoc
  • Host response to cancer. We employ pre-clinical and clinical research to develop and test new treatment strategies and to discover fundamental biological interactions between tumors and host organ systems.
Lab Website: janowitzlab.labsites.cshl.edu

CSHLCareers Cold Spring Harbor, New York


Description:

The Janowitz Laboratory at CSHL is seeking a highly motivated, creative, and interactive postdoctoral researcher with strong experimental and analytical skills to contribute to research on the connectivity of the host response to cancer. We employ pre-clinical and clinical research to develop and test new treatment strategies and to discover fundamental biological interactions between tumors and host organ systems.
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We are looking for candidates interested in developing their own research question in alignment with the interests and skills present in the laboratory and institution. The selected candidate will be provided significant resources, including access to state-of-the-art laboratory space and the opportunity to discuss science in a relaxed and diverse atmosphere defined by constructive critical appraisal. Opportunities to learn about model systems of disease, advanced microscopy, genetic engineering, new sequencing techniques, bioinformatics, translational science, and statistical analyses will be provided.



Qualifications/Preferred Skillsets:

Education: The applicant is expected to be in the process of completing or have recently completed a PhD degree with research experience in cancer biology, bioinformatics, biochemistry, biophysics, or immunology.
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Experience/Skills: The candidate must have a deep understanding of the requirement to test hypotheses experimentally to advance scientific knowledge. A strong track record of peer reviewed lead authorship publications is expected. Sound knowledge of metabolism, physiology, biochemistry, neuroscience, endocrinology, and immunology are required. We use animal models for research and, therefore, experience in working with animal models of disease is essential. Knowledge of computational analyses of large data sets is necessary for the work and candidates will be expected to demonstrate skills during the interview process.

Applications should explain the specific motivation of the candidate to apply for this postdoctoral post and, to be considered, candidates must also apply for this position via the CSHL website at: https://cshl.peopleadmin.com/postings/18496
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Founded in 1890, Cold Spring Harbor Laboratory is a world-renowned research and educational institution with programs in cancer, neuroscience, plant biology, genomics, and bioinformatics. CSHL is a private, not-for-profit institution in New York and has been home to eight Nobel Prize winners. Today, CSHL’s multidisciplinary scientific community is bolstered by more than 600 researchers and its Scientific Meetings & Courses Program, which hosts more than 9,000 scientists from around the world each year on its campus. Website: https://www.cshl.edu
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We offer a competitive salary and comprehensive benefits program, including medical and dental insurance, and access to an affordable and licensed on-site childcare center. In addition, CSHL Meetings and Courses program provides an opportunity for interacting with a broad range of researchers and exposure to timely advances in many areas of scientific research.
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You are required to be fully vaccinated for COVID-19 as a condition to your employment at the Laboratory, except in instances where you have a qualifying medical condition or sincerely held religious belief, practice, or observance that is contrary to receiving the vaccine. You will be required to provide proof of your vaccination on your first day of employment. For those individuals, who are unable to receive a vaccine due to access issues, they will be expected to receive the vaccine upon arrival in New York.
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CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, or protected veteran status. VEVERRA



Featured Publications:

1) Janowitz, T. (2018) Cancer: The Tumor-Driven Disease of the Host. Cell Metab, 28(1) pp. 5-6.
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2) Sng, C. C. T., O'Byrne, S., Prigozhin, D. M., Bauer, M. R., Harvey, J. C., Ruhle, M., Challis, B. G., Lear, S., Roberts, L. D., Workman, S., Janowitz, T., Magiera, L., Doffinger, R., Buckland, M. S., Jodrell, D. J., Semple, R. K., Wilson, T. J., Modis, Y. , Thaventhiran, J. E. D. (2018) A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway. J Allergy Clin Immunol, 142(1) pp. 311-314.e6.

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3) Casey, R. T., Giger, O., Seetho, I., Marker, A., Pitfield, D., Boyle, L. H., Gurnell, M., Shaw, A., Tischowitz, M., Maher, E. R., Chatterjee, V. K., Janowitz, T., Mells, G., Corrie, P. , Challis, B. G. (2018) Rapid disease progression in a patient with mismatch repair-deficient and cortisol secreting adrenocortical carcinoma treated with pembrolizumab. Semin Oncol,

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4) Flint, T. R., Jones, J. O., Ferrer, M., Colucci, F. , Janowitz, T. (2018) A comparative analysis of immune privilege in pregnancy and cancer in the context of checkpoint blockade immunotherapy. Semin Oncol,


Something about the PI: Cancer is a systemic disease. Using both laboratory and clinical research, the Janowitz group investigates the connections between metabolism, endocrinology, and immunology to discover how the body’s response to a tumor can be used to improve treatment for patients with cancer.Link to Application (if using external Application Portal): https://cshl.peopleadmin.com/postings/18496
Please include in Application :
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