Postdoctoral Fellow, University of California, San Diego

  • Postdoc
  • Neuroimaging biomarkers of Alzheimer's disease and brain aging
  • Applications have closed
Lab Website: emilie.reas

etreas La Jolla, CA, USA


Description:

The lab of Dr. Emilie Reas aims to develop neuroimaging-based biomarkers of brain aging and AD. Their primary focus is using structural, diffusion, and permeability MRI to examine the cellular and neurovascular changes that underlie cognitive decline in normal aging as well as in preclinical and prodromal Alzheimer’s Disease (AD). Her lab uses a multi-modal approach to evaluate how genetic, demographic, health, or lifestyle factors influence brain biomarkers and their associations with clinical and cognitive outcomes. Previously, they have demonstrated that measures of brain microstructure derived from advanced diffusion MRI predict cognitive decline and AD pathology, mediate normal cognitive aging, and are associated with vascular dysfunction. The lab is extending this work to understand how blood-brain barrier breakdown contributes to AD pathogenesis and relates to microstructural brain abnormalities and neuropathological burden. A parallel emerging focus of her research is assessing the synergy between risk for AD and neurological complications from COVID-19.
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We are looking for an enthusiastic postdoctoral fellow to join our team at the University of California San Diego School of medicine campus in La Jolla, CA. UC San Diego’s Department of Neurosciences has a rich, internationally acclaimed history for its contribution to the research of neurodegenerative diseases. Research studies of AD and other neurodegenerative disorders at UC San Diego are part of the clinical bench strength of the UC System. For the past 30 years, UC San Diego has been a leader in AD research and home to the prestigious Shiley-Marcos Alzheimer’s Disease Research Center (ADRC) and the Alzheimer’s Disease Cooperative Study (ADCS).


Responsibilities:

Postdoctoral positions are available in the following areas:
1) Development of novel neuroimaging (MRI / PET) biomarkers of AD or brain aging
2) Identification of genetic, demographic, health, or lifestyle determinants of cognitive aging or dementia
3) Associations of blood-brain barrier permeability with other AD biomarkers (MRI, PET, CSF, plasma, etc.)
4) Synergy between AD pathogenesis and neurological sequelae of COVID-19


Qualifications/Preferred Skillsets:

Requirements for the position include: a Ph.D. in neuroscience, cognitive science, psychology, or a related field. Demonstrable skill in neuroimaging (preferably MRI) data processing and analysis, proficiency in one or more programming languages (e.g. Matlab or Python) and strong statistical skills are highly desired. A background in cognitive function and/or neurodegenerative disease is highly preferred. The ideal applicant will have excellent verbal and written communication skills, as demonstrated by a strong publication record and conference presentations. Grant-writing experience and prior success at obtaining grant funding, as well as the ability to mentor and teach others, are highly desirable. The successful applicant should be collaborative, resourceful, and productive.
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To apply, please email a cover letter, CV, and contact information for 3+ references to Dr. Emilie Reas at ereas@ucsd.edu.


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