Postdoc – RNA Virus Replication and Host Interaction, Morgridge Institute for Research

  • Postdoc
  • The molecular mechanisms of replication and host interactions in positive-strand RNA viruses, which include coronaviruses and many other important pathogens.
Lab Website: virology

Morgridge_Inst Madison, WI, USA


The Ahlquist laboratory (Morgridge Institute for Research and University of Wisconsin-Madison Institute for Molecular Virology) is seeking highly motivated postdoctoral research associates to join and expand our studies of the molecular mechanisms of replication and host interactions in positive-strand RNA viruses, which include coronaviruses and many other important pathogens. Projects include multiple aspects of the structure, assembly, and function of viral RNA replication complexes, which are fascinating molecular machines and major targets for potentially broad-spectrum virus control (e.g., Unchwaniwala and Ahlquist [2020] Science; Unchwaniwala et al. [2020] PNAS; Nishikiori and Ahlquist [2018] Science Advances; Ertel et al. [2017] eLife). Our studies in these areas are developing and integrating new approaches in molecular genetics, biochemistry, cryo-electron microscopy, computational biology, and other areas.
Successful candidates will join a dynamic, multidisciplinary team with diverse backgrounds and expertise in a well-equipped, interactive research environment on the University of Wisconsin-Madison campus. They will find fertile project foundations, opportunities to collaborate with leading groups in and beyond UW-Madison, and support for growth in creative and critical thinking, vision, communications, and other areas essential for varied research careers. We offer an outstanding work environment built around multi-disciplinary approaches, state-of-the-art facilities, and team science. UW-Madison consistently ranks among the top U.S. research universities and the City of Madison among the ‘best places to live in the US’ with a diversity of cultural and outdoor opportunities. In addition to competitive salary, health benefits, etc., Morgridge postdoctoral positions also provide the rare advantage of retirement benefits. Reasonable accommodations may be made to enable individuals with disabilities to perform the primary duties.

Qualifications/Preferred Skillsets:

Candidates should have a PhD in biochemistry, biophysics, microbiology or another relevant area. They should also have a productive experimental record, strong initiative and a clear desire to spearhead innovative, substantial research advances. Excellent communications skills and the ability to work with a diverse research team are essential. Prior experience with viruses is appreciated but not required.
To apply visit:

Something about the PI: In his capacity as a UW-Madison professor, Paul holds faculty positions in the University’s Department of Oncology in the School of Medicine and Public Health, the Institute for Molecular Virology under the Office of the Vice Chancellor for Research, and the Department of Plant Pathology in the College of Agricultural and Life Sciences. He is also the Associate Director for Basic Sciences at the UW Carbone Cancer Center. Paul’s research group studies the molecular mechanisms of viral replication, virus-host interactions and viral pathogenesis, including virus-induced cancers.
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