Research Scientist (Research Associate), Icahn School of Medicine at Mount Sinai

  • Postdoc
  • Scientist
  • Technician/Research Asst.
  • Function of immune-related (inflammation) genes induced by steroid hormones in mammalian hematopoietic stem/progenitor cells and in erythropoiesis at steady-state and under conditions of stress.

New York, NY, USA


Description:

A full-time NIH-funded Associate Researcher position (equivalent to Research Assistant or Research Scientist) is available immediately to participate in research on the function of immune-related (inflammation) genes induced by steroid hormones in mammalian hematopoietic stem/progenitor cells and in erythropoiesis at steady-state and under conditions of stress.
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We use genetic mouse models, primary human progenitor cells, and molecular, cell biological, biochemical analyses. amd computational approaches in our research.
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The successful candidate will work closely with a senior member of the lab as well as other members of the group. This individual must be highly motivated, have good communication skills, and keep excellent records. It is important that she/he can work efficiently as part of a team. Within this context, the work will involve research leading to authorship on resulting publications. Possibility of independent research project for qualified individuals.
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The successful candidate will be involved in a diverse array of routine laboratory activities, with a core focus on: (1) cell culture and molecular and biochemical and cellular analysis of such cultures using flow cytometry, RT-PCR, and other approaches; (2) handling of laboratory mice, genotyping, and tracking of mouse colonies. Training will be provided as needed. The successful candidate will also aid in general lab organization, re-stocking common reagents and solutions and maintaining lab databases.


Responsibilities:

1. Conduct and design experiments independently under the direction of lab Principal Investigator (PI) and more senior lab members using advanced research techniques; perform basic molecular and cellular biology methods such as basic molecular subcloning and real-time RT-PCR, mammalian cell culture, mouse husbandry, flow cytometry, and microscopy. Must be able to read, understand, and interpret scientific literature relevant to the research.
2. Report research progress to PI orally, at laboratory group meetings, and in written progress reports and maintain a current knowledge of relevant literature.
3. Maintain good written laboratory records and contact with collaborators.
4. Summarize experimental data and assist in drafting publications under the direction of the PI. Assist the PI with publications by extracting and compiling moderate to complex research data from the relevant literature; assist in interpreting the data; write drafts of and edit manuscripts.
5. Master computer and technical skills necessary for experimental execution as well as data input and analysis.
6. Mentor and train less experienced research staff in research techniques and use of equipment.
7. Perform other related duties as assigned.


Qualifications/Preferred Skillsets:

Highly motivated, responsible individual with a B.S. in Biomedical Sciences (or equivalent). At least 1 year of independent, relevant work experience in a research lab is required, preferably on an independent project such as for a senior honors thesis. Must have experience with mammalian cell culture; must be willing to work with mice. A commitment of at least 2 years is required. Must be U.S. citizen or Permanent Resident; if already in U.S., must have visa valid for at least 1 more year.


Something about the PI: Margaret H. Baron, MD PhD, is Irene and Arthur M. Fishberg Professor of Medicine; Senior Associate Dean for MD/PhD Education and Co-Director of the MD-PhD Program; Program Director of an NIH-funded T32 Medical Scientist Training Program (MSTP); and a member of the Tisch Cancer Institute(TCI) and Black Family Stem Cell Institute (BFSCI). Dr. Baron is an established scientist who has over 30 years of continuous, independent NIH-sponsored research funding in hematopoiesis and gene regulation and a publication record spanning protein biochemistry, virology, cell biology, developmental biology, and stem cell biology. She is known for her work on the plasticity of the differentiated state, globin gene regulation, and developmental hematopoiesis.

Salary: Commensurate with experience, starting at $58,800.
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