Postdoctoral Associate, Weill Cornell Medicine

  • Postdoc
  • Immune responses in mothers & infants that contributes to vertical transmission of viral pathogens such as HIV, cytomegalovirus (CMV), Zika, Rotavirus, and SARS-CoV-2.
Lab Website: www.permarlabwcm.org

SalliePermar New York, NY, USA


Description:

The Permar Laboratory research focuses on both innate and adaptive immune responses to viral infections at the maternal-fetal interface and mucosal surfaces, with special emphasis on immune responses that are passed onto the neonate through the placenta and breast milk. Our lab investigates immune responses in both mothers and infants that contribute to impeding transmission of vertically transmitted viral pathogens, such as HIV, cytomegalovirus (CMV), Zika, Rotavirus, and SARS-CoV-2 and how these effective immune responses can be leveraged to design effective prophylactic and therapeutic vaccines. We use ex vivo human and nonhuman primate samples to test our hypotheses. We are looking for a talented postdoctoral scientist to take on an active leadership role in the growth of our laboratory, particularly in the area of defining and eliciting protective immune responses against neonatal pathogens.
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There will be extensive opportunities for career development including mentoring and leading research projects, presenting original research at meetings and national/international level conferences, publications, and writing grant applications. The lab is located in the Weill Cornell Medicine Belfer Research Building in the Department of Pediatrics at Weill Cornell Medicine in New York City, NY.


Responsibilities:

We are looking for motivated scientists to join our fast paced and growing team. Candidates should have the ability to work independently as well as in a collaborative research team. The candidate is expected to have strong written and verbal communication skills, an ability to establish clear goals and organize and prioritize work, and the ability and willingness to work with a diverse team of clinicians and scientists, including postdocs, students, and technicians.


Qualifications/Preferred Skillsets:

• Virology techniques including virus propagation and titering.
• Strong molecular biology skills to include Single genome amplification (SGA) of viruses, molecular cloning, DNA & RNA isolation, qPCR.
• Mammalian cell and tissue culture
• Multicolor flow cytometry
• Immunology techniques (ELISA, Viral neutralization assays, cytokine detection by ELISAs and/or flow, ELISPOT, CTL cloning)
• Experience working with Herpesviruses and RNA viruses, and a strong background in human immunology and/or T cell biology is highly advantageous but not required.


Something about the PI: As a pediatric scientist and the mother of two children, I am passionate about giving children the best possible start to a full and healthy life
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