Senior Research Assistant, Knight Cancer Institute, Oregon

  • Scientist
  • Technician/Research Asst.
  • Intersection of biomedical data science and cancer metabolic reprograming that occurs during cancer treatment.
Lab Website: knight-cancer-institute

Portland, Oregon


We are seeking a Senior Research Assistant to work at the intersection of biomedical data science and cancer metabolic reprograming that occurs during cancer treatment as part of the Thomas Lab. We seek to identify metabolic vulnerabilities that occur under selective pressure of treatment, which can then be exploited to eliminate tumor cells.
Function/Duties of Position:

The successful candidate will be creative and driven; able to analyze and apply computational tools to emerging genomic technologies to address basic and translational questions in our research area, including cancer metabolism, cancer therapeutics and biomarker discovery. Important findings will be further explored experimentally, both in our lab and through collaboration, with the ultimate goal of translating promising findings into clinical trials. We are looking for a highly-motivated individual, with a basic background in molecular/cellular biology and mathematics, who has a strong desire to learn and integrate biological and computational modeling techniques.
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-Data analysis using bioinformatics software
-Performs basic molecular biology techniques including functional cell assays, PCR, Q-PCR, cellular imaging, DNA/RNA extraction, Western blots, etc.
-Performs cell culture including drug treatments
-Assists in the development of new assays in clinical samples

Qualifications/Preferred Skillsets:

Bachelor’s Degree (4 yr.) with major courses in computational biology, molecular and cell biology or related field and at least 1 year of relevant laboratory experience.

Featured Publications:

Previous publications from our group include: Genes & Development 20, 2067-2084; Metabolites 5, 82; Cell 174: 758-769; Nature Medicine 12,122-127; Cancer Journal 15, 406-420; Science Translational Medicine 3(85): 85ra47; J Clin Oncol 36: 2492-2503; Cell Rep Med 2, 100267.

Something about the PI: Portlandia may or may not be reflective of us!
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