frbustos Sioux Falls, SD, USA
The Bustos Lab in the Pediatrics and Rare Diseases Group at Sanford Research has an opening for a Postdoctoral Fellow to investigate ubiquitin related signaling pathways that are disrupted in intellectual disabilities. This research will be carried out by using cutting-edge technologies to study signal transduction using pluripotent stem cells as a developmental model.
Please email Dr. Francisco Bustos Francisco.Bustos@sanfordhealth.org with a letter describing your experience and research interests, your CV, and names of three references. Informal enquiries are welcome.
The ideal candidate will have PhD in Cell Biology, Biochemistry, or related discipline and experience in cell culture and molecular biology. Prior experience in stem cell biology or protein biochemistry and a publication record in international peer-reviewed journals are desirable. Candidates from underrepresented backgrounds are strongly encouraged to apply.
A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne-Kalscheuer syndrome (2021) Bustos F, Espejo-Serrano C, Segarra-Fas A, Toth R, Eaton AJ, Kernohan KD, Wilson MJ, Riley LG, Findlay GM. Sci Rep. May 5;11(1):9560.
Functional diversification of SRSF protein kinase to control ubiquitin-dependent neurodevelopmental signalling (2020). Bustos F., Segarra-Fas A., Nardocci G, Cassidy A, Antico O, Davidson L, Brandenburg L, Macartney T, Toth R, Hastie J, Moran J, Gourlay R, Vargese J, Soares R, Montecino M, Findlay GM. Developmental Cell, 2020 Oct 10:S1534-5807(20)30757-7.
RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation (2018). Bustos F.*, Segarra-Fas A.*, Chaugule VK, Brandenburg L, Branigan E, Toth R, Macartney T, Knebel A, Hay RT, Walden H, Findlay GM. Cell Rep. 2018 May 8;23(6):1599-1611.