Research Associate, Protein Purification & Process Development

  • PhD Student
  • Postdoc
  • Scientist
  • Technician/Research Asst.
  • Research Associate to join the Protein Purification and Process Development function.
  • Applications have closed
Lab Website: www.amunix.com

San Francisco, CA


Description:

The Research Associate will join the Protein Purification and Process Development function and contribute to the performance of Amunix’s established purification processes, development and optimization of processes for new molecules, and support project-specific purification development strategies. This position heavily supports Amunix’s internal production and R&D efforts, and it interfaces internally with Molecular Biology, Fermentation Operations, and Analytical Chemistry as well as externally with partners both domestic and abroad. Initiative, ingenuity, flexibility, communication, and work ethic are paramount in this role.


Responsibilities:

-Perform bench-scale purifications using a range of chromatography as well as filtration methods
-Monitor progress using established assays such as HPLC, SDS-PAGE, spectrophotometry, LAL endotoxin
-Analyze, interpret, and communicate test results in an effective manner
-Thoroughly maintain experimental records through database and notebook entries
-Execute experiments to improve recovery, clarification, chromatography, and formulation processes
-Maintain process equipment, troubleshoot problems, and propose solutions
-Self-motivated, ability to work independently and within a cross-functional team
-Routinely update a cross-functional team on experimental plans and outcomes
-Clear, effective, timely communication is critical
-Desire to work within and maintain an open, collaborative environment is essential


Qualifications/Preferred Skillsets:

-Master’s of Bachelor’s degree in protein chemistry, biochemistry, pharmaceutical sciences, or similar
-2 years of work experience in a process development or manufacturing role
-Working knowledge and hands-on operating experience with state-of-the-art purification development tools and in-process analytical methods/screening tools
-Experience in Recovery, Chromatography, Formulation, Sterile & Aseptic processing
-Experience with purification and handling of metastable proteins is preferred
-Experience with cGxPs, DOE, and QBD is preferred
-Physical ability to lift up to 40 lbs and work at the lab bench for extended periods of time


Something about the PI: We work hard, play hard, and get stuff done
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