itchdoctor St. Louis, MO, USA
The Kim Lab is seeking a postdoctoral associate in the Department of Medicine and Center for the Study of Itch and Sensory Disorders. We have a wide range of projects exploring how the sensory nervous system communicates with the immune system to regulate sensation and inflammation a barrier surfaces such as the skin, lung, and gut. Techniques we employ include mouse modeling, calcium imaging of neurons, multidimensional flow cyotmetry and CyTOF, single cell RNA- and ATAC-seq, intravital 2-photon imaging, and intersectional genetics in mice.
MD/PhD or PhD with a solid publication record in neuroscience and/or immunology.
A Basophil-Neuronal Axis Promotes Itch. Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS. Cell 2021. PMID: 33450207
Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis. Mack MR, Brestoff JR, Berrien-Elliott MM, Trier AM, Yang TB, McCullen M, Collins PL, Niu H, Bodet ND, Wagner JA, Park E, Xu AZ, Wang F, Chibnall R, Council ML, Heffington C, Kreisel F, Margolis DJ, Sheinbein D, Lovato P, Vivier E, Cella M, Colonna M, Yokoyama WM, Oltz EM, Fehniger TA, Kim BS. Sci Transl Med 2020 PMID: 32102931
Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F, Kim BS, Dong X. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity 2019. PMC6531358
Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ, Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML, Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen ZF, Hu H, Davidson S, Liu Q, Kim BS. Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell 2017. PMID: 28890086